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Consider a B12 shot if you often feel run-down, struggle with concentration, have mood fluctuations, or want a natural boost without relying on caffeine or stimulants

However, a very small percentage of B12 from a supplemental dose is absorbed by passive diffusion, rather than by intrinsic factor, such that vegans can make up for taking B12 only once per day, or even only once per week, by taking larger doses than normally provided by food

For patients who have done the work on diet and exercise and still carry clinically significant visceral fat, it represents one of the few pharmacological tools with both the mechanism and the data to address the problem directly

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